Peritoneal fluid in young women with endometriosis
Many blood substances are present in peritoneal fluid due to their derivation from the transudation of blood through the peritoneal surface. Ectopic endometriotic lesions can also change the medium to contribute to the definition of the local environment of the…
Key Points Lay SummaryIs continuous hormonal treatment safe and healthy method for endometriotic patients?
One of the studies related to the search for new markers in pathophysiologic causes of endometriosis is circulating microparticles and their subset "tissue factor". In response to damage, activation, or apoptosis, these microparticles are found in human plasma, urine, saliva,…
Key Points Lay SummaryDienogest versus combined oral contraceptives treatment in postoperative endometriosis care
Dienogest is a synthetic progestin derivative, like oral contraceptives, used to prevent endometriosis recurrence after surgery. Randomized clinical trials verified a significantly higher reduction in endometriotic lesions, clinical symptoms, and improved quality of life obtained when dienogest was given to…
Key Points Lay Summary2023 MedicalConferance: Pros and cons of hormonal interventions for endometriosis - Sarah Berga, MD
Prof. Berga, MD., who is the Chair of Ob&Gyn at Jacobs School Medicine and Biomed Sciences, presented this speech at the 2023 EFA Medical Conference. Dr. Berga explains that the primary goals of endometriosis treatment are to reduce pain and improve quality…
Key Points Lay SummaryWhat causes pelvic pain? Androgens or estrogens?
A comparison between women and men reveals that women suffer more pelvic pain. This reality raises the possibility of the pain-relieving effect of testosterone or androgens. It would be a wise solution to investigate how androgens affect pain at different…
Key Points Lay SummaryAn Overview on Treatment of endometriosis
There are different guidelines by different gynecological societies for the diagnosis and treatment of endometriosis, which is an extremely complex illness. Kalaitzopoulos and Samartzis et al. from Switzerland worked on and compared six national and two international widely used guidelines to…
Key Points Lay SummaryEffects of Hormonal Contraceptives on Endometriosis Pain
There is no difference between the oral progestin dienogest and combined oral contraceptive pills in managing pain and increasing quality of life in women with endometriosis, according to the results of a randomized, double-blind, placebo-controlled clinical trial. However, there was…
Key Points Lay SummaryPharmacological Therapy for Endometriosis Pain
The negative effects of endometriosis on women’s quality of life are indisputable. Women who suffer from endometriosis might have to deal with problems in many aspects such as psychological, sexual, social, and economic. Pain which is one of the most…
Key Points Lay SummaryWomen reject using hormonal drugs for endometriosis, an accelerating need for nonhormonal medications
Although the pathophysiology of endometriosis is poorly understood, endocrine drugs are widely used for reducing inflammation and patients’ symptoms. Burla and colleagues aimed to evaluate the patients’ thoughts and expectations about the endocrine drugs which are used in the treatment…
Key Points Lay SummaryPostoperative long-term estro-progestin therapy for endometrioma
After the removal of ovarian endometriomas, the major concern is the high recurrence rate of symptoms and endometriotic cysts. The estimated recurrence rate of endometriomas is up to 50% at 5 years after surgery. To prevent the recurrence, postoperatively long-term…
Key Points Lay SummaryThe peculiarity of adolescent endometriosis
Recent studies showed the prevalence of endometriosis in adolescents with chronic cyclic or acyclic pelvic pain is about 60-70%. Moreover, all stages of endometriosis, including deeply infiltrating endometriosis can be found in this population. Gubbels et al. from the Department…
Key Points Lay SummaryDiagnosis and treatment algorithm for endometriosis
Endometriosis is a chronic and progressive disease that affects 25-30% of women between 25-35years, clinicians commonly experience during their gynecologic practice. However, the diagnosis is still late or sometimes incorrect, and this creates severe health problems and worse outcomes. A…
Key Points Lay SummaryThe efficacy of combined hormonal contraception on pelvic pain in endometriosis patients
Chronic pelvic pain, which is experienced by more than 33% of endometriosis patients, constitutes a significant challenge for patients and physicians. A new study that appears in the journal Human Reproduction Open has explored the prevalence of endometriosis patients with a history…
Key Points Lay SummaryAdolescent dysmenorrhea and future endometriosis
Dysmenorrhoea is typically classified as primary, or secondary due to underlying pathologies like fibroids, endometriosis, adenomyosis or uterine anomalies. Generally, long-term dysmenorrhea is present in endometriotic patient's anamnesis, but until recently, the research to clarify this connection remained retrospective. Knox et…
Key Points Lay SummaryEndometriosis and female pelvic pain in all aspects
Endometriosis is defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity. The prevalence of the disease ranges between 6-10% in reproductive-aged women. However, endometriosis is more frequently encountered in women with chronic pelvic pain and…
Key Points Lay SummaryOral Contraceptives and Low-Cost Progestins to Reduce Endometriosis-Associated Pain
Most women with endometriosis-associated pain did not feel the need to use expensive progestin or undergo surgery. Instead, they were satisfied with a low-cost progestin to treat their symptoms. This is according to a study published in the journal Fertility…
Key Points Lay SummaryWhich Endometriosis Treatment is Better: NETA or Extended-cycle OC (Seasonique®)?
Scala et al. recently shared the findings of their patient preference prospective study in a journal article titled “Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique®) in the treatment of endometriosis symptoms: A prospective open-label comparative study,” which was published in the…
Key Points Lay SummarySwitching to a Low-Cost Progestin May Help Reduce Endo Pain When Oral Contraceptives Won’t Work
The majority of women with endometriosis-associated pain were satisfied to have switched to a treatment with norethisterone acetate or NETA, a synthetic, orally active progestin, when their oral contraceptive was ineffective, found a study published in the journal Reproductive Sciences.…
Key Points Lay SummaryThe Most Cost Effective Medical Treatment to Prevent Recurrent Endometriosis
A new study conducted in China found that a class of drugs called Gonadotropin-releasing hormone agonists (GnRH-a) is more cost effective for the treatment of recurrent endometriosis despite the fact that they are more expensive than oral contraceptives. The results…
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